Mineral oil emulsion



Patented Aug. 1, 1933 UNITED STATES MINERAL OIL EMULSION Harry Noonan,to The Drug White Plains, N. Y., assignor Products Co., Inc., LongIsland City, N. Y., a Corporation of New York No Drawing. ApplicationNovember 6, 1930 Serial No. 493,922

3 Claims. (01. 107-56) The invention relates to mineral oils and moreparticularly to emulsions of highly refined mineral oils for internaluse.

An object of the invention is to provide such 5 a composition which ispalatable and pleasant,

one that has great powers of internal lubrication, and one in which theconsistency of the mineral oil is not afiected.

A further object is to provide a composition which is readily misciblewith the intestinal contents and assists in the formation of a softfecal mass, and which contains no sugar.

It has been discovered that mineral oils and more particularly thehighly refined mineral oils in common use at the present time forinternal administration as lubricants may be emulsified by a jelly madefrom psyllium seed, agar agar and gelatin by intimate mixture therewithand by passing through a colloid mill. The intimate mixture of thepsyllium seed jelly and mineral oil may be accomplished by shaking,mixing and grinding or homogenization and thereby eliminate the use ofsuch emulsifying agents as Acacia or tragacanth which are ordinarilyused in forming emulsion of mineral oils in aqueous vehicles.

The psyllium seed jelly and agar agar act to greatly enhance thelubrication value of the emulsion and the gelatin acts to increase thestability of the composition.

In the emulsion the mineral oil may be present in varying proportions.In practice it has been found that an emulsion containing 70% of mineraloil by volume is very satisfactory for internal use. The proportion ofthe elements forming the jelly may also be varied and other materialshaving similar properties to those mentioned may be used .to form thejelly. The following proportions of the above named materials in con- 40junction with a 70% volume content of mineral oil have been found toform a suitable colloidal emulsion: 6 of 1% of psyllium seed jelly, of

1% of agar agar, 7/100 of 1% of gelatine, 5%

of glycerine, and a water quantity of 100% with sodium benzoate as apreservative. Such a colloidal emulsion provides a homogeneous mass,

which is both palatable and pleasant. Moreover, the agar agar ingredientin conjunction with the mineral oil serves an additional function ofbeing a laxative.

As heretofore stated the emulsion may be readily formed by mixing themineral oil with the psyllium seed jelly base and then passing themixture through a colloid mill which causes complete dispersion of theoil and presents a finished product in a colloidal form. Emulsionsformed in accordance with this invention are cream-like in appearanceand taste, are palatable and effective in internal use as a mechanicallubricant and remedy for constipation. The mineral oil used ispreferably one which has been highly refined for internal use.

The mineral oil emulsion may be made as heretofore stated, or theingredients may be varied. For somewhat obstinate cases of constipationwith gastro-intestinal hyperacidity, a mechanical lubricant which ismildly laxative is desirable and one which contains no sugar. Anemulsion containing the following ingredients has been found to work outwell in practice: mineral oil 50%; milk of magnesia 8%; glycerin 5%; and20% of jelly containing psyllium seed, agar agar and sodium benzoate.This emulsion is colloidal in form and pleasant to take. It normalizesperistalsis by modifying the intestinal bulk and consistency so that thefeces are easily expelled.

In cases of chronic constipation or intestinal stasis, more pronouncedlaxative action is often required in addition to lubrication. The

following is another way of mixing the ingredients to accomplish thisresult: mineral oil 70%, caromel 2 /270 and a jelly made from psylliumseed of 1%, agar agar i o% of 1%, gelatine 7/100 of 1%, glycerine 5% andwater quantity sufiicient ad 100% with sodium benzoate as apreservative, phenolphthalein a laxative and any suitable flavoringsubstance.

It is to be noted that the emulsion of your! applicant is anoil-in-water type of colloidal emulsion with a homogeneous and finedispersion.

In the preparation of the colloidal oil-in-water emulsion, use is madeas above mentioned of the colloid mill which intimately mixes the highlyrefined mineral oil together with the jelly of the ingredients andproportions thereof, as before set forth, into a homogeneous colloidalemulsion wherein the dispersed phase, namely oil,- is both uniform andfine in size.

I claim:

1. A laxative comprising a colloidal oil-inwater type mineral oilemulsion comprising a homogeneous and fine dispersion of substantially70% by volume of a highly refined mineral oil in 105 a jelly comprisingsubstantially of 1% of psyllium seed, substantially of 1% agar agar andsubstantially 7/ of 1% gelatine.

2. A colloidal oil-in-water type mineral oil emulsion comprising ahomogeneous and fine dispersion of substantialLv 70% by volume of ahighly refined mineral oil in a jelly comprising substantially of 1% ofpsyllium seed, substantially of 1% agar agar and substantially 7/ 100 of1% gelatine, the above said proportions being adapted to form anemulsion of a homogeneous and line dispersion.

3. A colloidal oil-in-water type mineral oil

